If DNA bridges persist between chromosomes during cell division, chromosomes are abnormally segregated, leading to genetic ...

In fact, Watson and Crick were worried that they would be "scooped" by Pauling, who proposed a different model for the three-dimensional structure of DNA just months before they did. In the end ...

Abstract Faithful chromosome segregation requires the removal of all DNA bridges physically linking chromatids before the completion of cell division ...

However, incomplete DNA replication or chromosome ... The study was conducted using the model organism Caenorhabditis elegans, whose LEM-3 protein is evolutionarily conserved as ANKLE1 in humans.

If DNA bridges remain between chromosomes after cell division, chromosomes become improperly segregated, resulting in genetic ...

ATX-559, a first-in-class oral DHX9 inhibitor, is being evaluated in a Phase 1/2 study with a focuson advanced or metastatic ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

May 20, 2025) The fundamental processes that govern neural development are complex and, as findings by scientists at St. Jude ...

Annual Financial Analyst Conference May 21, 2025 9:00 AM ETCompany ParticipantsAlexandra Steiger - Global Head of ...

Genome informatics includes methods to analyse DNA sequence information and to ... It compares cell types and states between models, and harmonizes cell annotations through mapping to primary ...

The treatment of leukemia among children could be made more precise with fewer side effects with the help of more accurate ...

Researchers have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through lice rather than ticks, and how it gained ...