In women with advanced (metastatic) breast cancer, aromatase inhibitors including those in current clinical use show a survival benefit when compared to other endocrine therapy.

Conclusions Treatment with the selective TYK2 inhibitor deucravacitinib was well tolerated and resulted in greater improvements than placebo in ACR-20, multiplicity-controlled secondary endpoints and ...

Leflutrozole, an aromatase inhibitor, is being tested in a phase 2 trial for male infertility due to low testosterone levels. The trial will enroll 200 patients, assessing leflutrozole's impact on ...

Background: Aromatase inhibitor-induced musculoskeletal syndrome (AIMSS) has emerged as a major cause of treatment discontinuation in hormone receptor-positive patients treated with aromatase ...

The Low-Testosterone Symptoms to Look Out for—and How to Handle Them If your libido’s dried up and your energy levels are dipping, it could be a hormone problem. Here's what to do if it is.

Future study designs evaluating cognitive dysfunction in patients on aromatase inhibitors should include a multifaceted approach of neuropsychiatric testing and neurological functional imaging.

Table 1. Summary of medical therapy (chemotherapy and aromatase inhibitors) and measurements of cognitive functioning (neuropsychological testing and functional imaging) and potential confounders ...