The impulse of an action potential causes the release of acetylcholine from synaptic vesicles (each containing about 10,000 molecules of acetylcholine) diffusing across the 20-nm gap to the ...

Researchers have developed a groundbreaking computational model that provides detailed insights into the vesicle cycle, a key process in synaptic transmission. Their model predicts parameters ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles. Now, ...

Vesicle cycle model reveals inner workings of brain synapse Advanced modeling system sheds new light on the synaptic vesicle cycle, essential in human brain function Date: May 28, 2025 Source ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are transmitted between nerve cells using molecular containers called vesicles.

Researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport neurotransmitters in the brain.

Imaging synaptic vesicles in 3D Max Delbrück Center researchers have used cryo-electron tomography to uncover new details of the molecular structure of synaptic vesicles, which help transport ...

eLife assessment This study presents valuable observations on a potential role of creatine (Cr) as a novel neurotransmitter. While the data provide compelling evidence that Cr is present in synaptic ...

Abstract The discovery of a new neurotransmitter, especially one in the central nervous system (CNS), is both important and difficult. We have been searching for new neurotransmitters for 12 years. We ...

Findings provide a structural framework for understanding the physiology and pharmacology of neurotransmitter packaging by synaptic vesicular transporters.

Mechanisms to separately regulate synaptic vesicle release and recycling Chemical synapses transmit information within the nervous system.

Neuron anatomy. Close-up of a Chemical synapse Neuron anatomy. Close-up of a Chemical synapse, Synaptic vesicle with neurotransmitter, and Receptors. Strucure of Synaptic cleft. Vector poster ...