Acetylcholine (Ach) is a ... Here, it builds up in the synaptic terminal where it recombines with acetyl molecules. ACh is transported into the end of neurons (synaptic vesicles) ...

The impulse of an action potential causes the release of acetylcholine from synaptic vesicles (each containing about 10,000 molecules of acetylcholine) diffusing across the 20-nm gap to the ...

An action potential reaching the motor-nerve terminus triggers the release of acetylcholine from synaptic vesicles. Acetylcholine then rapidly diffuses across the gap to the postsynaptic end plate ...

One intracellular interaction that may mediate synaptic vesicle clustering is binding of neurexin to synaptotagmin 9, a synaptic vesicle protein. Another is the binding of neurexin to CASK 10 , a ...

Mechanisms to separately regulate synaptic vesicle release and recycling Date: July 19, 2021 Source: Johannes Gutenberg Universitaet Mainz Summary: ...

The Rho-Linked Mental Retardation Protein OPHN1 Controls Synaptic Vesicle Endocytosis via Endophilin A1. Current Biology , 2009; DOI: 10.1016/j.cub.2009.05.022 Cite This Page : ...

Young and his team first confirmed that the proteins play several key roles in ensuring that synaptic vesicles which contain ...

Since most molecules are too large to directly pass through ... Südhof showed that deletion of Munc18-1 in mice leads to a complete loss of neurotransmitter secretion from synaptic vesicles.

Researchers have achieved something long thought almost impossible - counting the molecules of the neurotransmitter glutamate released when a signal is transferred between two brain cells. ...

Along the way the group had many interesting surprises. For example, the quantity of glutamate in a synaptic vesicle, calculated at roughly 8000 molecules' worth, has been revealed to be much greater ...