How do we think, feel, remember, or move? It all depends on transmission of chemical signals in the brain, carried and released by molecular containers called vesicles. In a new study, researchers ...

How do we think, feel, remember, or move? These processes involve synaptic transmission, in which chemical signals are ...

2 Astrocytes maintain the chemical environment, regulate blood flow, and support synaptic ... At the synapse, neurons communicate chemically. When an action potential reaches the axon terminal ...

First, in many cases, individual connections between two neurons are comprised of multiple synaptic contacts, the number varying with the connection type. Second, the synapses that mediate these ...

The reconstructed vesicle cycle model provides critical insights into synaptic transmission, advancing neuroscience and ...

LICONN is the first technology beyond electron microscopy capable of reconstructing brain tissue with all the synaptic connections ... the team made use of the chemical and physical properties ...

A recent Nature Communications study explored how synaptic vesicle (SV) composition changes with age and α-synuclein (αSyn)-related disease. The researchers focused on the role of αSyn in ...

Presynaptic NMDA receptors can shape timing-dependent long-term depression in a way that departs from their classic postsynaptic role.

We rely on synaptic plasticity—the strengthening and modulation of connections between these neurons—to facilitate learning and memory. Synapses, or the junctions where neurons communicate ...

An unprecedented international effort to decode how cells manage the transport of chemical substances has culminated in four groundbreaking studies This decade-long project provides the first ...

Sankaet Pathak’s last startup, fintech Synapse, filed for bankruptcy in 2024 amid issues with partner Evolve Bank & Trust. Tens of millions of dollars in deposits made by consumers, mostly ...