By putting a carbon atom in place of a core oxygen, chemists constructed an opioid that blocks pain with less respiratory ...

Green and Sustainable Chemistry aims to design chemical products and processes that reduce or eliminate the use and ...

Irreversible inhibition as a therapeutic modality has come of age over the previous decade. With minimal theoretical guidance for the design of an irreversible modulator, empirical optimization ...

The Journal of Medicinal Chemistry is pleased to present its latest Drug Discovery Collection, this time dedicated to contributions from Czechia. Czechia (and former Czechoslovakia) has a long ...