ACHV's cytisinicline shows best-in-class efficacy and safety for smoking cessation. Click here to find out why ACHV stock is ...

The application of machine learning algorithms to predict the mechanism of action (MoA) of drugs can be highly valuable and enable the discovery of new uses for known molecules. The developed methods ...

Natural products have played a pivotal role in malaria chemotherapy progressing from quinine and artemisinin to ozonide-based compounds. Many of these natural products have served as template for the ...

However, there are certain circumstances in which succinylcholine is contraindicated, including suspected hyperkalemia, known prior adverse reactions, concern for head injury, neuromuscular ...

A short-cut review was carried out to establish whether rocuronium is as effective as succinylcholine at facilitating laryngoscopy during rapid sequence intubation (RSI). A total of 94 papers was ...

Patients with type 2 diabetes mellitus are at a higher risk of developing heart failure compared with the healthy population. In recent landmark clinical trials, sodium-glucose co-transporter 2 (SGLT2 ...

REGISTER NOW Epigenomic Tools for Decoding Drug Mechanism of Action Broadcast Date: Thursday, July 17, 2025 Time: 2:00 pm PT, 5:00 pm ET, 23:00 CEST First Name* ...

The cellular composition and underlying spatiotemporal transformation processes of subchondral bone in osteoarthritis (OA) remain unknown. Herein, various cell subsets from tibial plateau of patients ...

This study evaluated the growth-inhibiting properties of CIP against Babesia spp. and investigated the mechanism of CIP on B. gibsoni. The half inhibitory concentration (IC 50) values of CIP against ...

The mechanism of action (MoA) of a clickable fatty acid analogue 8-(2-cyclobuten-1-yl)octanoic acid (DA-CB) has been investigated for the first time. Proteomics, metabolomics, and lipidomics were ...