Cµ, immunoglobulin heavy chain constant region; J558 H, the V H region of the J558 myeloma cell line; +, linker-ligated genomic DNA template; c, control linker-ligated template consisting of ...

These 163 immunoglobulin heavy and light chain rearrangements were translated and analyzed for potential HLA-binding peptides using prediction software.

"Studies show that [multiple] myeloma is associated with more than 400 canonical somatic mutations per patient, and the most commonly mutated genes include immunoglobulin heavy chain and light ...