“But when it enters E. coli, the linear DNA gets converted to a circular molecule because the viral DNA has sticky—or cohesive—ends,” said Mertz. She hypothesized that this also happened with ...

Other modes of nucleic acid interaction aside from sticky ends are available. For example, Tecto-RNA molecules 6, held together by loop–loop interactions, or paranemic crossover (PX) DNA, where ...

DNA has the potential for assembling networks with a variety of geometries. Although short pieces of double-strand DNA (below about 50 nm) essentially form a linear stack, intricate spatial structures ...

Recent work1,2,3 has demonstrated the self-assembly of designed periodic two-dimensional arrays composed of DNA tiles, in which the intermolecular contacts are directed by ‘sticky’ ends. In a ...

And for many years biologists have used DNA for its recognition properties, especially exploiting the sticky ends in genetic engineering. A sticky end occurs when one strand of the helix extends ...

Scientists have constructed ''DNA droplets'' comprising designed DNA nanostructures. ... Each side of a Y-motif comprises a short sticky end that interacts with other 'compatible' sticky ends.

Bacterial biofilms stick together using a DNA glue – the surprising discovery suggests new treatments for conditions like cystic fibrosis ...

The structural difference in DNA cleavage—Cas12a generates staggered cuts with sticky ends—may explain the divergence in repair outcomes.

To work, the sticky-ends have to contain complimentary DNA sequences. DNA is made up of four bases, or "letters," that combine in specific ways: A always pairs with T and G with C.

Immune cells may help painful gallstones grow by ejecting sticky nets of DNA around the crystals that form in bile – a finding that could lead to new treatments. Close. Advertisement.