Early trials found that both garadacimab and sebetralstat were safe when used in patients living with hereditary angioedema, ...

A new statement from leading heart and blood vessel experts in Europe is providing clinical guidance for treatments to ...

The blood is exposed to collagen in the activated vascular endothelium, initiating coagulation. Platelets respond to the site of injury and become activated, releasing substances such as growth ...

Updated results from the phase 3 XTEND-1 trial were presented at ISTH, once again comparing the therapy to patients' previous treatment with clotting factor replacement.

THN391 has the potential to be a first-in-class antibody that can block fibrin-mediated neuroinflammation without affecting coagulation pathways, and recently completed a phase 1ba trial in ...

It is clear that these interactions are important for the control of normal coagulation and influence the efficacy of heparin and heparin-based therapeutics. In addition to neutralization, the ...