In a real-life quantification of CP-CML patients treated with first-line imatinib, dasatinib, or nilotinib (320, 24, and 53 patients, respectively, with a median follow-up of 9 years for patients ...

You may hear this called Philadelphia positive leukaemia. Dasatinib is a type cancer growth blocker called a tyrosine kinase inhibitor. It works by blocking a signal that tells leukaemia cells to grow ...

Dasatinib (Sprycel) is another TKI that targets the BCR-ABL protein. This drug is a pill taken once a day with or without food. Dasatinib can be used as the first treatment for CML, but it can also be ...

The company’s efforts to revive its portfolio amid generic competition for legacy drugs like Revlimid, Pomalyst, Sprycel and Abraxane are impressive. Drugs like Reblozyl, Breyanzi, Camzyos and ...

CML study IV is a randomized 5-arm trial that compares imatinib 400 mg vs imatinib 800 mg vs ... had been switched to second-generation TKIs (dasatinib: 1, nilotinib: 1) because of imatinib ...

This important work advances our understanding of CHMP5's role in regulating osteogenesis through its impact on cellular senescence. The evidence supporting the conclusion is convincing and the ...

We examined whether senescent cells are maintained during differentiation of COPD airway epithelial cells at the air–liquid interface and examined the role of the senolytic combination of dasatinib ...

Hypertriglyceridemia (triglycerides 200–499 mg/dL) is relatively common in the United States, whereas more severe triglyceride elevations (very high triglycerides, ≥500 mg/dL) are far less frequently ...

When you purchase through links on our site, we may earn an affiliate commission. Here’s how it works. As Whoop's latest fitness tracker (along with the Whoop 5.0), I was excited to see what the ...

Abraxane sales were cut in half; Sprycel revenues dropped by a few points more than that. And generics are expected to further cut into its business over the next few years. Yes, the Street is ...