Investigators examined the comparative effectiveness of SGLT2 inhibitors and GLP-1 receptor agonists in a real-world setting.

Islets of Langerhans are heterogeneous cell aggregates containing β-, α-, δ-, and PP cells, which secrete insulin, glucagon, somatostatin (SST), and pancreatic polypeptide, respectively.

We employed the pancreatic clamp technique [11] using somatostatin to block the endogenous secretion from the islets while substituting insulin and/or glucagon levels by infusions designed to ...

Inhibiting the hormone somatostatin could one day be a new treatment option to prevent low levels of blood glucose in patients with type 1 diabetes, according to results of recent study in mice ...

Researchers found that blocking somatostatin restores glucagon release in type 1 diabetes, potentially preventing severe hypoglycemia. The study highlights the relationship between pancreatic ...

Summary Researchers at the University of Gothenburg found that blocking somatostatin restores glucagon release in type 1 diabetes, potentially preventing severe hypoglycemia. The study highlights the ...

Inhibiting the hormone somatostatin may be a new treatment strategy to prevent dangerous blood glucose drops in type 1 diabetes.

Glucagon has the opposite effect in the body to insulin, which lowers blood glucose. Both hormones are produced in the pancreas. People with type 1 diabetes have a lack of insulin but also glucagon.

Glucagon has the opposite effect in the body to insulin, which lowers blood glucose. Both hormones are produced in the pancreas. People with type 1 diabetes have a lack of insulin but also glucagon.

Inhibiting the hormone somatostatin may be a new treatment strategy to prevent dangerous blood glucose drops in type 1 diabetes. This has been shown by a study conducted at, among others, the ...

Findings indicate that excessive somatostatin inhibits glucagon secretion in type 1 diabetes, offering a novel target for hypoglycemia management strategies.

Five years after implantation, they found that the tissue was well supplied with blood vessels and consisted of islets of cells that produced insulin, glucagon and somatostatin, all the hormones a ...