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demonstrating fully automated solid phase peptide synthesis. The process begins with swelling Tentagel S resin in DMF, preheating and Fmoc deprotection using 20% Piperidine in DMF. A reduction in ...
particularly in the context of solid phase peptide synthesis (SPPS), the webinar introduces a transformative approach toward achieving sustainability. This work combines, for the first time, the use ...
While the allyloxycarbonyl (Alloc) protecting group has played a key role in solid-phase peptide synthesis (SPPS), providing access ... We report metal-free, on-resin Alloc removal using readily ...
This new LPPS technology materially reduces solvent demand and the need for excess reagents compared to standard solid-state peptide synthesis processes ... peptides are then assembled in liquid phase ...
This new LPPS technology materially reduces solvent demand and the need for excess reagents compared to standard solid-state peptide synthesis ... in liquid phase, using a convergent fragment ...
Using preparative HPLC (LC-1 SHIMADZU ... and DIC–oxyme was used as the reaction coupling system. The target staple peptides were obtained by Fmoc solid-phase synthesis, and the S5/R8 amino acid side ...
To formulate a peptide or protein, you need to perform a chemical synthesis using mainly a solution-phase synthesis (SPS) or a solid-phase synthesis (SPPS). However, due to these compounds' complexity ...
the largest Solid-Phase Peptide Synthesis (SPPS) Manufacturing facility worldwide. After kicking off capital investments in early 2023, CordenPharma successfully completed a series of upgrades and ...
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