Solid-phase methods are widely used for the synthesis of biological molecules such as peptides, nucleic acids ... by mechanochemical anionic activation using a lithium(0) wire followed by addition ...

Two pentapeptides are produced using this new technology. The purity of the peptides produced by MEPS is higher than that of peptides produced by solid-phase synthesis, under the same conditions. This ...

The use of synthetic oligonucleotides and their mimics to ... Covalent postsynthesis or solid-phase conjugation of peptides to oligonucleotides offers a possible solution to these problems. As ...

for large-scale oligonucleotide manufacturing - into its large-scale peptide synthesis platform, the PeptiPro®. This enables shorter changeover times between batches while maintaining user safety ...

Enliven Therapeutics has decided against taking its phase 1-stage solid tumor drug into further development next year in order to keep resources flowing toward its leukemia candidate. The Colorado ...

FIRDAPSE boosts Catalyst's strong Q1 2025 results, beating forecasts. With 15–20% growth projected, see why analysts rate ...

Targeting to evaluate IDE849 (SHR-4849) in SCLC, NETs, and other DLL3-upregulated solid tumors, and in combination with IDE161/PARG to potentially enhance durability Targeting to present clinical ...

Phase 1 trial of TIM-3 inhibitor cobolimab monotherapy and in combination with PD-1 inhibitors nivolumab or dostarlimab (AMBER). This is an ASCO Meeting Abstract from the 2022 ASCO Annual Meeting I.

The Innovus+ platform incorporates Innovus synthesis and Innovus implementation capabilities, all integrated into one unified environment for outstanding ease of use and power, performance, and area ...

today announced that it has enrolled the first subject in the RECLAIM Phase 2 trial evaluating the efficacy and safety of pemvidutide in subjects with Alcohol Use Disorder (AUD). Pemvidutide is a ...

“Thanks to the FDA, food companies will have even more options they can use as they switch from synthetic colors to natural colors,” Faber said via email. “While it’s good news that the ...