siRNAs loaded in an Argonaute protein then target complementary single-stranded RNA (ssRNA ... 5′ overhang–containing dsRNA molecules. For example, slicing of an mRNA or a ssRNA guided ...

Current setbacks cannot prevent gene-editing companies from advancing closer to “one-and-done” cures and new products.

Q1 2025 Earnings Call Transcript May 9, 2025 Kymera Therapeutics, Inc. beats earnings expectations. Reported EPS is $-0.82, expectations were $-0.92. Justine Koenigsberg: Good morning, and welcome to ...

Beam Therapeutics and Verve Therapeutics have each built their lead candidates on a technique billed as a safer alternative ...

"All bacteria have double-stranded DNA, but viruses have different kinds of structure — there are DNA genomes, RNA genomes, double-stranded, single-stranded …" Anantharaman told Live Science.

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

Ribonucleic acid, also called RNA, is a molecule present in all living cells. It plays a critical role in transmitting ...

In Biology 101, we learn that RNA is a single, ribbon-like strand of base pairs that is copied from our DNA and then read ...

In the new study, the researchers used RNA silencing, a natural defence mechanism found in plants. When a virus infects a plant, it introduces double-stranded RNA (dsRNA), which is a red flag for ...

The FDA granted the designation to CRD-002, a single stranded anti-sense oligonucleotide ... or halt disease progression through targeted RNA-based modulation. Orphan Drug Designation is granted ...

This suggests that targeting high SHAPE-high Shannon G4 regions could be a promising approach against RNA viruses. Lastly, the manuscript identifies 73 single-stranded regions with high SHAPE and low ...