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Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not ...
RNA degradation is an essential process for maintaining cellular homeostasis, regulating both the quantity and quality of RNAs in the eukaryotic cell. RNA degradation typically occurs by exonuclease ...
Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).
For instance, he was the first to discover the order of the three major components of a single nucleotide (phosphate-sugar-base); the first to discover the carbohydrate component of RNA (ribose ...
Prostaglandin E2 (PGE2), a bioactive lipid derived from arachidonic acid, mediates a broad range of physiological processes through four G protein-coupled receptor (GPCR) subtypes: EP1–EP4 ...
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