Breast cancer often relapses in distant organs even when complete regression of primary tumors is achieved after initial ...

Learn how doctors may eventually be able to tell whether your cells are aging prematurely without needles, blood tests, or ...

Scientists use electric fields to detect aging 'zombie' cells without dyes or labels, offering a breakthrough for ...

New research reveals that aging isn't just a local cellular process—it can spread throughout the body via the bloodstream.

For the first time in the world, a Korean research team discovered how cellular aging can spread systemically through the bloodstream—offering new ...

Mammary gland fibroblasts are highly plastic and transition through distinct states during development and disease. A new study by Pascual et al (2025) provides a comprehensive single-cell atlas of ...

Fibroblasts come in 11 different shapes and sizes, three of which are distinct to senescent skin cells, the researchers found. Only one subtype of senescent fibroblast, which the researchers named ...

Fibroblasts produce the internal scaffolding that give skin tissues their structure. They pushed the fibroblasts towards senescence by damaging their DNA, which happens with aging.

Senescent skin cells, often referred to as zombie cells because they have outlived their usefulness without ever quite dying, have existed in the human body as a seeming paradox, causing inflammation ...

Reference: “Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts” by Pratik Kamat, Nico Macaluso, Yukang Li, Anshika Agrawal, Aaron Winston, Lauren Pan, ...

Both UV- and drug-induced senescence models showed similar upregulation of AP2A1, as did senescent epithelial cells, indicating that AP2A1’s role in senescence extends beyond just replicative ...