The San Francisco 49ers struggled under stormy skies as they lost to the Indianapolis Colts 30-18 in their Sunday night football game at Levi’s Stadium in Santa Clara. It was the most inclement ...

INDIANAPOLIS -- The San Francisco 49ers seek their first win of the season as they face the Indianapolis Colts in Week 5. In order to do so, Pierre Garçon will have to get San Francisco's offense ...

Some speed from Carson Wentz on the scramble up the gut there, driving through the defense. Took a shot at the end but picked up a big first down. Colts now approaching the red zone.

The Indianapolis Colts finally figured out how to deliver a knockout punch Sunday. They capitalized on turnovers, made big plays at timely moments and, yes, even managed to protect a late lead.

Watch the San Francisco 49ers' top plays vs. the Indianapolis Colts during Week 7 of the NFL 2021 season. Watch the best plays from the Kansas City Chiefs in the AFC Championship Game against the ...

In Week 5, the San Francisco 49ers head east to take on the Indianapolis Colts. The game takes place on Sunday, Oct. 8 at 10:00 a.m. PT at Lucas Oil Stadium. Here are all the ways you can watch ...

Watch the highlights from Super Bowl LIX between the Kansas City Chiefs and the Philadelphia Eagles during the 2024 NFL season. Watch Kansas City Chiefs quarterback Patrick Mahomes' best plays ...

The San Francisco 49ers have been trying to fill the void left by former Oregon Ducks defensive tackle DeForest Buckner for years. Buckner was traded by the 49ers to the Indianapolis Colts for a ...

The Indianapolis Colts and San Francisco 49ers are ready to duke it out this Sunday night after completing their week of practice. The Colts ruled out a few starters including two from the ...

The San Francisco 49ers struggled under stormy skies as they lost to the Indianapolis Colts 30-18 in their Sunday night football game at Levi’s Stadium in Santa Clara. It was the most inclement ...

An interesting matchup between a pair of two-win teams on Sunday Night Football sees the San Francisco 49ers, fresh off the bye week, take on the Indianapolis Colts who are coming off their ...