Ever since the San Francisco 49ers traded DeForest Buckner to the Indianapolis Colts, they have lacked a physical presence in the middle of their defense. The 49ers attempted to address the issue ...

May 21 (UPI) --Jim Irsay, the principal owner of the Indianapolis Colts since the death of ... NFL // 1 week ago San Francisco 49ers sign punter Thomas Morstead May 28 (UPI) -- San Francisco ...

May 20 (UPI) --The San Francisco 49ers and Fred Warner agreed to a ... NFL // 2 weeks ago Indianapolis Colts owner Jim Irsay dies at age 65 May 21 (UPI) -- Jim Irsay, the principal owner of ...

The San Francisco 49ers are looking to bounce back from a year most fans would prefer to forget. The usually unstoppable offense of Brock Purdy, Christian McCaffrey, Deebo Samuel Sr., ...

That's what many people think about the Indianapolis ... as the Colts have one primetime game scheduled-- Week 16 at Lucas Oil Stadium against the San Francisco 49ers on Monday Night Football ...

The Indianapolis Colts have their 2025 ... Kansas City Chiefs, and San Francisco 49ers will be tough. Also, the Colts have two meetings with the reigning AFC South champion Texans, against which ...

When and who do the Indianapolis Colts face in their primetime matchup? That game this year will come in Week 16 against the San Francisco 49ers on Monday Night Football and will be played at Lucas ...

Against all odds, the San Francisco Giants won the World Series in 2010, 2012 and 2014. After an off-year that followed a Super Bowl appearance, Brock Purdy and the 49ers wouldn’t mind a similar ...

Check out the full 2025 San Francisco 49ers schedule as well as a record prediction: Eric D. Williams: After having the toughest schedule in the league last year, San Francisco has the easiest ...

The Indianapolis Colts will have one primetime game this season, just as they did in 2024. That game this year will come in Week 16 against the San Francisco 49ers on Monday Night Football and ...