The San Francisco 49ers struggled under stormy skies as they lost to the Indianapolis Colts 30-18 in their Sunday night football game at Levi’s Stadium in Santa Clara. It was the most inclement ...

INDIANAPOLIS -- The San Francisco 49ers seek their first win of the season as they face the Indianapolis Colts in Week 5. In order to do so, Pierre Garçon will have to get San Francisco's offense ...

An interesting matchup between a pair of two-win teams on Sunday Night Football sees the San Francisco 49ers, fresh off the bye week, take on the Indianapolis Colts who are coming off their ...

In Week 5, the San Francisco 49ers head east to take on the Indianapolis Colts. The game takes place on Sunday, Oct. 8 at 10:00 a.m. PT at Lucas Oil Stadium. Here are all the ways you can watch ...

Every NFL team can use a dynamic offensive weapon like San Francisco 49ers do-it-all wide receiver, Deebo Samuel; the Indianapolis Colts included. NFL.com's Ian Rapoport broke news that the 49ers ...

6-yard touchdown while facing Harbaugh, his college coach, for the first time, and the Indianapolis Colts defeated the San Francisco 49ers 27-7 on Sunday. Trent Richardson scored a 1-yard ...

The San Francisco 49ers have been trying to fill the void left by former Oregon Ducks defensive tackle DeForest Buckner for years. Buckner was traded by the 49ers to the Indianapolis Colts for a ...

Veteran cornerback Charvarius Ward is going to play the 2025 season with the Indianapolis Colts after spending the previous three seasons with the San Francisco 49ers. According to ESPN's Adam ...