Sec22b is closely apposed to the plasma membrane SNARE syntaxin1. Sec22b forms a trans-SNARE complex with syntaxin1 that does not include SNAP23/25/29, and does not mediate fusion. Insertion of a ...

Intracellular protein trafficking and secretion of proteins into the extracellular environment are sequential and tightly regulated processes in eukaryotic cells. Conventionally, proteins that are ...

Multi-C2 domain-containing ferlin proteins have key roles in membrane repair and vesicle trafficking, as well as links to ...

Researchers from the Göttingen Cluster of Excellence Multiscale Bioimaging (MBExC) have uncovered the 3D structure of the ...

Vaccinex's proprietary ActivMAb ® Technology enables expression of functional, properly folded complex ... fusion protein technology that enables direct incorporation of multi-pass membrane ...

We thank Ms. Emily Lopes for help with blinding and Drs. Bill Wickner, Shumin Tan, Hesper Rego, and Dan Hebert for valuable discussions. We also thank the directors of the University of Massachusetts ...

Laboratoire de Biologie et Modélisation de la Cellule, CNRS, UMR 5239, Inserm, U1293, Universite Claude Bernard Lyon 1, Ecole Normale Supérieure de Lyon, 46 allée d’Italie, 69364 Lyon, France Centre ...

Comprehensive Orthopedics Department, the Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an, Shaanxi 710004, P. R. China State Key Laboratory for Manufacturing Systems Engineering, Xi’an ...

further filtering and integration of interactions obtained from BioGRID and CORUM to allow visualization of protein complexes. Our study should contribute to the general understanding of the ...