However, the minimal number of SNARE complexes needed for membrane fusion is not known. Here we show unambiguously that one SNARE complex is sufficient for membrane fusion. We performed controlled ...

Fusion has been thought to occur via the spontaneous zipper-like assembly of the SNARE protein complex, which may distort and pucker the membrane, physically forcing the lipids in the membrane ...

Accepter SNARE proteins then form, allowing fusion with another vesicle membrane. How this mechanistically ... physiological model is that a tethering complex (termed HOPS) is interacting with ...

According to a popular model, membrane fusion occurs when soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins on one membrane form a complex with SNARE proteins on ...

It does that by talking to the membrane fusion protein." More information: Chanwoo Lee et al, Exocyst stimulates multiple ...

To induce membrane fusion, the proteins combine to form a SNARE complex in a four helical bundle, and NSF and α-SNAP disassemble the SNARE complex for reuse. In particular, NSF can bind an energy ...

SNAP-25 is one component of the SNARE core complex which also includes Syntaxin ... with syntaxin 1 and is thought to help restrict fusion of vesicles to specific sites of the plasma membrane.