The NSF homolog Sec18 initiates fusion of yeast vacuoles by disassembling cis‐SNARE complexes during priming. Sec18 is also required for palmitoylation of the fusion factor Vac8, although the ...

The heterotrimeric synaptic soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) complex, consisting of the synaptic vesicle-associated membrane protein 2 (VAMP2 ...

Dr Turner is Co-Lead for the NTU Research Theme: Diabetes, Chronic Diseases & Ageing. His research focuses on understanding the causes of diabetes and inflammatory diseases, and in identifying new ...

SNARE functions during membrane docking and fusion are regulated by Sec1/Munc18 (SM) chaperones and Rab/Ypt GTPase effectors. These functions for yeast vacuole fusion are combined in the six‐subunit ...

The inset depicts the formation of the heterooctameric exocyst complex at the target membranes by the dynamic assembly of its subcomplexes (SC), SC-1 and SC-2 which mediates tethering of the vesicles, ...