We hypothesize that PCBP2 is an intrinsic aging factor of BMSCs and regulates the senescence of hBMSCs through a ROS- and FGF2-dependent pathway. Cells were inoculated into 24-well plates, and when ...

Exercise for improving cancer prognosis Van der Schoot et al 26 Anti-inflammatory: physical exercise may reduce cancer therapy–induced formation of ROS, preventing vascular damage and subsequent ...

We hypothesize that PCBP2 is an intrinsic aging factor of BMSCs and regulates the senescence of hBMSCs through a ROS and FGF2 dependent pathway. The hBMSCs cells were lysed with RIPA, and the protein ...

Cells subjected to various senescence-eliciting insults accumulated ... which fed the formation of SASP and reactive oxygen species (ROS). Iron detection by MRI could enable non-invasive ...

LIU Guanghui’s group at the Institute of Zoology (IOZ) of CAS has shed light on the role of ER-generated ROS in cell senescence. The study establishes the relationship between oxidative protein ...

Figure 2. Effects of ROS on plant leaf senescence. Numerous abiotic and biotic stresses like salinity, heat, cold, nutrients, heavy metals, insects, pathogens, etc., resulting to the accumulation of ...

We also discuss the role of NO in the modulation of phytohormones during senescence and the significance of NO-ROS cross-talk during programmed cell death and senescence. Phytohormones are chemical ...

Neutrophils cause telomere dysfunction both in vitro and ex vivo in a ROS‐dependent manner. In a mouse model of acute liver injury, depletion of neutrophils reduces telomere dysfunction and senescence ...

The molecular mechanism of cellular senescence was further explored by detecting reactive oxygen species (ROS) levels and culturing cells with a conditioned medium. We revealed the cellular senescence ...

The accumulation of ROS has been linked both to aging and cellular senescence, so the team looked at the relationship between DAO and ROS in causing cellular senescence. When DAO was knocked down ...