The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

The structure of its larger subunit revealed that the ribosome is a ribozyme with RNA at the heart of its enzymatic activity that catalyses peptide bond formation. Numerous initiation, elongation ...

The team first measured how atomic nuclei in the drug respond to magnetic fields using solid-state nuclear magnetic resonance ... Level Structure of an Amorphous Glucagon-Like Peptide-1 Receptor ...

Oxidoreductases are key enzymes in biocatalysis, but their dependence on the cofactor nicotinamide adenine dinucleotide ...

Researchers have observed hydrogen and deuterium molecules in tiny spaces called picocavities using advanced spectroscopy. This study reveals unique differences between the molecules due to quantum ...

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

BEIJING-Families in China are changing, as the world’s second-largest economy grows from strength to strength, causing relationships between parents and their adult children to evolve accordingly.

The influence of piezoelectric phase volume fraction and composite aspect (thickness/width) on resonance characteristic of square 1-3-2 piezoelectric composite plate has been researched. In addition, ...

Prolyl oligopeptidase B from Galerina marginata (GmPOPB) has recently been discovered as a peptidase capable of breaking and forming peptide bonds to yield a cyclic peptide. Despite the relevance of ...

† Department of Applied Chemistry, Kyung Hee University, Deokyoungdaero 1732, Gyeoggi-do 446-701, Republic of Korea ‡ Department of Chemistry, KAIST, Daehak-ro 291, Yusung-ku, Daejeon 305-701, ...