The principal brain target of all antipsychotic drugs is the dopamine D 2 receptor; in fact, the older traditional antipsychotics, such as haloperidol, chlorpromazine, pimozide, fluphenazine and ...

Remoxipride can be used in the treatment of psychosis and behavioural disturbances. [157] Recommended dosages in elderly patients are 50-100 mg/day. [197] ...

Methods— This was a 12-month, parallel-group, randomized, multicenter, double-blind, placebo-controlled study. Eligible patients were ≥60 years of age with a Montreal Cognitive Assessment test score ...

A dose of the D2/D3 receptor antagonist, remoxipride, that completely prevents this agonist-mediated depression has no impact on the profile of persistent (>24 h) LTP that is elicited at these ...

Animals were treated with remoxipride 30 min before starting the trials on day 4. Here also, we first verified that the animal cohorts that were subsequently treated with vehicle (n = 9) or ...

The perinatal period is associated with an increased risk of severe mental disorders. We summarise the evidence regarding the epidemiology, risk factors, and treatment of severe mental illness in ...

This review compares the effects of zotepine to other second generation antipsychotic drugs. Three trials suggest that the efficacy of zotepine may be comparable to risperidone and remoxipride. The ...