Therefore, RaPID enables both characterization as well as discovery of protein–RNA interactions in a variety ... RNA prepared using RNeasy Plus mini kit (Qiagen) according to the manufacturer's ...

After considering a number of different approaches to analyze RNA-protein interactions both directly in the cell (in vivo) and isolated in a test tube (in vitro), the biologists settled on an in ...

This tends to be specific to the platform that is being used for sequencing, and many companies will offer a library preparation kit. You will need to consider ... of post-transcription modifications, ...

Profacgen, a leading provider of cutting-edge genomic services, has recently updated its CLIP-Seq service offering that leverages the latest irCLIP-Seq technology, providing researchers with a ...

CLIP (cross-linking immunoprecipitation) is a technique for studying RNA-protein interactions and locating specific RNA modifications. After UV cross-linking the RNA-protein complex, ...

and RNA-protein interactions (RPI) in cellulo with unprecedented performance and enables the screening of molecules that can modulate these interactions. Iktos, a leading European company in GenAI ...

as well as their capacity to regulate RNA-protein interactions. RBPs play a crucial role in circRNA biogenesis and function, with specific proteins like QKI, SP1, FUS, ADAR1, and DHX9 shown to ...

A key contribution to this event is protein-RNA interaction." The physical-chemical mechanism that leads to the formation of biomolecular condensates is the liquid-liquid phase separation and some ...

RNA-protein interactions (RPIs) are therefore critical regulators of diverse cellular processes, implicating them in the pathogenesis of diseases such as cancer, neurodegenerative disorders, and ...

The image on the laptop screen shows the 3D structure of a large protein-free RNA complex — one of three unprecedented structures their research collaboration discovered using cryo-EM at SLAC.

They found many were RNA-binding proteins (RBPs), in keeping with their involvement in pathogenic protein aggregation and their known interactions with tau (May 2016 news; reviewed by Maziuk et al., ...