Nucleic acids (DNA or RNA) are polymers of nucleotides – each nucleotide consists of a pentose ... Now, a photoswitchable DNA structure-specific, small-molecule ligand enables reversible ...

Northwestern Medicine investigators have discovered that a novel long noncoding RNA (lncRNA), which are usually 200 ...

Bone is a common site for metastasis of solid cancers, but histological and molecular features of bone metastases are not ...

The expression of symptoms of viral infections is a byproduct of complex virus-host molecular pathways. These remain largely ...

A unique feature of HR is that it repairs the damage to the DNA in a highly accurate way. In eukaryotic cells (those with a ...

The molecular pathways involved in antiviral defenses and counter-defenses in host-pathogen systems remain unclear. Researchers have used Neurospora crassa as a model organism to explore how RNA ...

Currently, the researchers are using CRISPR-TO to move endogenous RNAs – RNA molecules that are naturally produced within the ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

The yeast nuclear endonuclease Rnt1 has a well-characterized role in the maturation of many ncRNA precursors. However, the scope and consequence of its function in mRNA degradation pathways is much ...