In this article, we describe a method to determine the quaternary structure of membrane proteins and to follow its retention during protein handling. It is well known that classical size-exclusion ...

Unlike the original periodic table, which organized the chemical elements, the new periodic table organizes protein complexes, or more precisely, quaternary structure topologies. Though there are ...

The quaternary protein structure refers to the orientation and arrangement of subunits in proteins with multi-subunits. This is only relevant for proteins with multiple polypeptide chains.

structural biology makes use of some fundamental concepts related to the hierarchical assembly of proteins and nucleic acids (such as macromolecule structure; primary, secondary, tertiary and ...

The structure of a protein is hierarchically arranged, from a primary to quaternary structure. The wide variation in amino acid sequences accounts for the different conformations in protein structure.

Proteins have four levels of structure: primary (amino acid sequence), secondary (local folding patterns like alpha helices and beta sheets), tertiary (overall 3D shape), and quaternary (assembly of ...