Uric acid can be controlled by eating ... Deficits in B vitamins, particularly B6, B12, and folate, which aid in the effective metabolism of homocysteine, are frequently linked to it.

likely becomes essential due to impairment of de novo purine synthesis. Other genes with strong environmental lethality or viability included several other players in nucleotide synthesis (DHODH, UMPS ...

biotin metabolism, folate biosynthesis, thiamine metabolism, and the one-carbon pool by folate. Lipid metabolism pathways, including biosynthesis of unsaturated fatty acids, linoleic acid metabolism, ...

Endogenous intracellular allosteric modulators of GPCRs remain largely unexplored, with limited binding and phenotype data available. This gap arises from the lack of robust computational methods for ...

CNS Drugs. In press. Ordonez LA, Wurtman RJ: Folic acid deficiency and methyl group metabolism in rat brain: Effects of L-DOPA. Arch Biochem Biophys 160:372-376, 1974. Bottiglieri T, Hyland K ...

or folate when it is found naturally, is one of the body's required water-soluble vitamins. Vitamin B9 is essential to cell division, DNA synthesis, and the development of healthy red blood cells.

Increasing evidence support that cellular amino acid metabolism shapes the fate of immune cells; however, whether aspartate metabolism dictates macrophage function is still enigmatic. Here, we found ...

The liver is the central hub for cholesterol metabolism and the distribution center for lipoproteins. Hepatocytes assemble and secrete VLDL (very-low-density lipoprotein) particles, which are ...