Mechanism of action describes the process by which a molecule, such as a drug, functions to produce a pharmacological effect. A drug’s mechanism of action may refer to its effects on a ...
The catalytic intermediates of the reaction catalyzed by DpgC are hypothetical, and their electronic and protonation states and their energies are not known. The future challenges will be to ...
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Neutron Scattering Reveals Enzyme SecretsThe locations of the hydrogen atoms determine protonation states of specific chemical groups inside the enzyme’s active sites. Thus, they provide information on the electric charge distribution ...
Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, California 94025, United States SSRL, SLAC National Accelerator Laboratory, Menlo Park, California 94025, United States ...
Enveloped viruses encode ion-conducting pores that permeabilize the host cell membranes and mediate the budding of new viruses. These viroporins are some of the essential membrane proteins of viruses, ...
Lassa virus (LASV) glycoprotein complex (GPC) contains retained stable-signal peptide (SSP), glycoprotein 1 (GP1), and glycoprotein 2 (GP2). Through serial passaging of LASV with inhibitors, adaptive ...
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