Protein synthesis by the ribosome can ... the addition of an artificial tag to the C terminus. However, the eukaryotic mechanism performs ribosome splitting, nascent-chain tagging and nascent ...

More information: Natalia Khalatyan et al, Ribosome customization and functional diversification among P-stalk proteins ...

Northwestern Medicine scientists have uncovered new details about how poxvirus hijacks its host's protein synthesis machinery ...

terminus, the team called the extensions CAT tails. Together, the evidence was convincing. “What all of this was saying was that we were getting a totally unprecedented mechanism for ribosome-mediated ...

Elongation, a crucial step in the translation process of protein synthesis, gets disrupted by amino acid sequences with an abundance of N-terminal ... in cells by ribosomes. This diverse set ...

Scientists observe ribosomal cooperation that prevents pauses in protein synthesis, revealing new dynamics for cellular ...

The researchers found that a nascent two-domain immunoglobulin protein folds at its N-terminal end while its C-terminal end is still stuck in the ribosome exit tunnel, the birth canal for baby ...

A joint research group of Tokyo Institute of Technology (Tokyo Tech) and Kyoto Sangyo University has discovered that a protein, during its synthesis, may destabilize the structure of the ribosome ...

Polypeptide chains are formed where the ribosome, the protein synthesis machinery, resides on a copy of the DNA sequence (messenger RNA). It starts polymerizing amino acids one by one by selecting ...