Procalcitonin is formed by the cleavage of pre-procalcitonin with the aid of an endopeptidase enzyme. The level of procalcitonin in the serum of a healthy individual is usually below 0.01 µg/L.

Procalcitonin emerged as a strong diagnostic marker that may boost early SAP detection when combined with predictive models.

"Procalcitonin can help to diagnose sepsis, especially in cases where there is uncertainty," said Ferrer. And the level can be used to determine the severity of the patient's condition.

Procalcitonin is the precursor to the hormone calcitonin, which has been widely studied due to the pivotal role which it plays in calcium homeostasis. Yet PCT has itself been the subject of numerous ...

A recent study conducted by Austin Health, Australia, has revealed that the serum level of procalcitonin can be a strong indicator of bacterial co-infection with COVID-19.

Among 140 patients included in the analysis, 56.4% had serum procalcitonin levels of less than 0.5 ng/mL, while 43.6% had levels of 0.5 ng/mL or higher.

Daily assessment of procalcitonin (PCT), rather than standard care alone, led to patients spending significantly less time on antibiotics cumulatively in the first 28 days (9.8 days vs 10.7 days ...

Credit: Shutterstock. Researchers assessed the effects of a procalcitonin-guided protocol in reducing antibiotic prescription rates among patients hospitalized with COVID-19 infection.

Procalcitonin-guided care reduced antibiotic use without increasing the risk for infection among patients with acute pancreatitis compared with standard care, according to research published in ...

Join us to discover how Procalcitonin testing improves patient outcomes, contributing to antibiotic stewardship efforts. Talks will cover essential topics such as assay selection, validation, ...

Objective: Procalcitonin has emerged as a promising infection marker, but previous reports from small-sized studies suggest nonspecific elevation of procalcitonin after pediatric heart surgery. As ...