Unraveling the Complexities, Risks, and Latest Breakthroughs in Diagnosis and Treatment Introduction to Coxsackievirus: Classification and Virology Epidemiology and Global Distribution Patterns ...

Somatic hypermutation (SHM) of immunoglobulin variable (V) regions modulates antibody-antigen affinity is initiated by activation-induced cytidine deaminase (AID) on single-stranded DNA (ssDNA).

The paranemic crossover as a cohesion motif is an attractive avenue for tecto-RNA because of the programmability of Watson−Crick basepairing and the reversibility of binding without strand ...

The authors investigate the influence of local dynamics and allosteric regulation on guide RNA binding affinity and DNA cleavage specificity through molecular dynamics simulations, advanced NMR ...

Department of Chemistry, Division of Biochemistry and Molecular Biology, Hamburg University, Martin-Luther-King-Platz 6, 20146 Hamburg, Germany, Institute of Crystallography, Free University of Berlin ...

We verified their reliability in single-cell RNA sequencing (scRNA-seq ... MiRNA inhibitors are chemically modified double-stranded oligonucleotides that can specifically bind to and inhibit ...

In this phase 2a, open-label, single-arm study in patients with hormone receptor-positive, HER2-positive advanced or metastatic breast cancer, we observed that the combination of the HER2-targeted ...