Sustainable materials—powered by sunlight and living microbes—that remove pollutants from water, release oxygen into a wound ...

Modified polymer could help people with PEG allergies Tweaking the polyethylene glycol layer around lipid nanoparticles could prevent rare reactions to drugs, including some COVID-19 vaccines by ...

The use of antisense oligonucleotides (AS ODNs) to inhibit the expression of specific mRNA targets represents a powerful bioengineering strategy for inhibition of gene expression. Cationic lipids and ...

Where would carbon-based life be without carbon? There are 118 known chemical elements, but carbon is the fourth most abundant and perhaps the most important to human life. Everywhere you look, ...

This article examines viral and non-viral vectors in gene therapy, highlighting their mechanisms, advantages, and limitations ...

Varying number of polymer chain copies were then inserted to a pre-equilibrated DOPC membrane (300 lipids in total) as indicated by the mol fraction reported in Figure 4H,I and Figure 4-figure ...

Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) in mice's lungs.

Researchers describe their advanced lipid-polymer nanoparticle that can hold mRNA in a stable form for nebulization and deliver it effectively as aerosol droplets to the lungs of mice. Challenges in ...

More information: Zwitterionic Polymer-Functionalized Lipid Nanoparticles for the Nebulized Delivery of mRNA, Journal of the American Chemical Society (2024). DOI: 10.1021/jacs.4c11347 ...

FOR IMMEDIATE RELEASE “Zwitterionic Polymer-Functionalized Lipid Nanoparticles for the Nebulized Delivery of mRNA” Journal of the American Chemical Society Most people don’t enjoy getting shots for ...

Zwitterionic Polymer-Functionalized Lipid Nanoparticles for the Nebulized Delivery of mRNA. Journal of the American Chemical Society, 2024; DOI: 10.1021/jacs.4c11347 ...