Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) into mice's lungs.

Researchers outline their improved lipid-polymer nanoparticle for holding mRNA that is stable when nebulized and successfully delivers aerosols (liquid droplets) in mice’s lungs. An improved lipid ...

Insight into the Mechanisms Driving the Self-Assembly of Functional Interfaces: Moving from Lipids to Charged Amphiphilic Oligomers. Journal of the American Chemical Society , 2019; 142 (1): 290 ...

Modified polymer could help people with PEG allergies Tweaking the polyethylene glycol layer around lipid nanoparticles could prevent rare reactions to drugs, including some COVID-19 vaccines ...

Morphology and Physical Properties of Hydrophilic-Polymer-Modified Lipids in Supported Lipid Bilayers, Langmuir, 34(24), 7201-7209. 10.1021/acs.langmuir.8b00870 Journal Langmuir ...

Polymer nanoparticles may be the answer. With virtually unlimited options for chemical features, “you can design bespoke delivery vehicles easier than with a lipid-based system,” says Sean ...

Our world-class facilities and dedicated team allow us to deliver top-tier solutions for lipid and polymer nanoparticle formulations, as well as drug product manufacturing.

Zwitterionic Polymer-Functionalized Lipid Nanoparticles for the Nebulized Delivery of mRNA. Journal of the American Chemical Society , 2024; DOI: 10.1021/jacs.4c11347 Cite This Page : ...

A study in the Journal of the American Chemical Society reports steps toward making inhalable mRNA medicines a possibility. Researchers outline their improved lipid-polymer nanoparticle for ...