Using CRISPR to correct the mutations behind polycystic kidney disease could counter some of the damage the condition causes ...

Healio: How did you come to participate in a pig-to-human kidney transplant ... that we went down the path of developing the Parsons model, which is a model in which we’ve leveraged human ...

It provides nutrients and oxygen to the fetus via the umbilical cord, acting like a gut, kidney, liver ... It shows that in guinea pigs, the therapy boosted placental function and delivery ...

Purespring bottles up $105M series B to bring kidney disease gene therapy to the clinic In a mouse model of IgA nephropathy, mice given PS-002 had lower levels of complement deposited in their ...

In 2020, a team led by UW scientist Dhanu Shanmuganayagam used gene editing to create a Wisconsin Miniature Swine model for xenotransplant studies. In a research building next to UW Hospital, kidneys ...

The same gene-edited pig kidney and thymus were used in that procedure ... of those who participated in our series of decedent model studies, this moment in transplantation would not have been ...

They both helped to develop a pig thymus–kidney concept with the intent of reducing the amount ... "Without the generosity and altruism of those who participated in our series of decedent model ...

She and her team at UAB actually helped to lay the groundwork for the medical victory with the first transplant in a pre clinical human model. “It’s really being able to do those pig kidney ...

For the model, the Yucatan miniature pig breed was specifically selected as an ideal donor owing to organ sizes comparable to human organs. Kidneys from the porcine model were initially ...

The pig kidney — provided by biotech company co-founded by HMS ... A multi-center-based trial would go a long way toward establishing the research efficacy for this model.” It could turn out, for ...

The team transplanted pig kidneys into more than 20 monkeys ... Montgomery added that the nonhuman primate model continues to be controversial in terms of how well its results will translate ...