Given its novel mechanism of action and proven efficacy ... For HER2-positive breast cancers, additions included pertuzumab, ado-trastuzumab emtansine, and neratinib. The CDK4/6 inhibitors ...

The question of putative mechanisms of action continues to haunt psychopharmacology. Put simply, we know these drugs work, but we have very little idea how. We make guesses based on the ...

The US Food and Drug Administration has approved the use of a novel painkiller as an effective treatment for short-term ...

Copy number variants (CNVs) arise by homologous recombination (HR) between repeated sequences (recurrent CNVs) or by non-homologous recombination mechanisms that occur throughout the genome (non ...

But sometimes you don’t want that! Sometimes you just want to escape the increasingly insane world out there into an action movie. Netflix has made a few of their own, but the bulk of the best ...

Despite the impact of the pandemic on cancer care, Perjeta grew 17% to CHF 2.9 billion ($3.2 billion) in the first nine months of 2020, now just fractionally behind Herceptin which declined 31% to ...

All physicians are faced with the challenge of how to help patients with no approved therapies for their diseases. What are ...

A teacher at Drakensburg Secondary School in South Africa is under investigation for allegedly cutting off a Hindu student's religious thread. The South African Hindu Maha Sabha has condemned the ...

In line with that, our review highlights the well-accepted mechanisms of action and resistance to the therapy and discusses the progress that has been made toward successfully overcoming this ...

The present article presents an in-depth review of recent breakthroughs in treatments for wound healing. It delves into the molecular mechanisms behind this process, explores traditional treatment ...

Pts with event, n (%) 198 (54.7) 20 (58.8) ...