Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During ...

Structure’s technology platform uses computational techniques that its says enables the visualization of three-dimensional protein structures and their interactions with a small molecule.

Researchers have long known that glycosaminoglycan-binding proteins (HBPs) help control vital processes like cell growth, ...

Researchers led by Université de Montréal pathology and cell-biology professor Marc Therrien have identified major structural ...

The unfolded protein response (UPR) is a crucial signaling network that preserves endoplasmic reticulum (ER) homeostasis, impacting both health and disease. When ER stress occurs, often due to an ...

is enhanced in peptides with a collapsed, folded structure. Interdisciplinary researchers at the Beckman Institute for Advanced Science and Technology combined single-molecule experiments ...

Livagen peptide, a short-chain molecule derived from thymic tissues, has garnered attention recently for its intriguing ...

Healthy cells are constantly breaking down proteins and building up new ones with the help of enzymes aptly named unfoldases, ...

However, some nascent peptides interact with the ribosomal tunnel and rearrange the internal structure ... as well as the distinct molecular mechanism of translation stalling and regulation ...

Studies suggest that the unique structure of PTD-DBM ... DBM-based interventions. PTD-DBM peptides represent a versatile and promising compound for various molecular biology and development ...

Once proteins, larger molecular complexes, or organelles have been labelled ... The basis for this work were peptides with a coiled structure, which were described in a structure database. The ...

Changes in the spatial structure of proteins can also be easily detected with ONE microscopy. In a collaboration with colleagues from Göttingen and Kassel, molecular protein aggregates, which are ...