Several reaction mechanisms have been proposed for peptide bond formation ().The peptidyl transferase reaction occurs through nucleophilic attack of the α-amino group of aminoacyl-tRNA on the ...

The ribosome therefore uses a substrate-induced fit mechanism to facilitate peptide bond formation and exclude hydrolysis, similar to that proposed for several enzymes, including hexokinase 4.

Peptide bond formation is one of the key chemical transformations in the field of prebiotic chemistry. It is regarded that peptides played an important catalytic role in the formation of other ...

A novel peptide appears to enhance a natural mechanism for protecting stressed brain cells and improve cognitive function following cardiac arrest, scientists report.

Noradrenaline (NA) is an important monoamine neurotransmitter in the nervous system. The noradrenaline transporter (NET) located on the presynaptic membrane can transport NA into presynaptic neurons.

Despite many years of study, the mechanism(s) and disease relevance of Abeta toxicity remains unresolved. Our current studies center around our characterization of a variant Abeta peptide that has a ...