In the study, scientists used CRISPR/Cas9 to edit tumor-infiltrating lymphocytes (TILs) — immune cells that naturally enter tumors. By switching off a gene known as CISH, the edited TILs gained ...

Researchers at the University of Minnesota have completed a first-in-human clinical trial testing a CRISPR/Cas9 gene-editing technique to help the immune system fight advanced gastrointestinal (GI ...

And of course, zombie cells. The technical term is senescent cells. They’re damaged and unable to repair themselves. They’re also more likely to linger in the body as we age — like zombies ...

Stomach acid, if given the opportunity, would happily digest our own tissues. It’s released by parietal cells that are tucked within folds along the tunica mucosa lining of the stomach.

In the stomach, so-called parietal cells are responsible for acid production. They react not only to the body's own messenger molecules, but also to bitter-tasting food constituents such as caffeine.

Metabolic regulator ERRγ governs gastric stem cell differentiation into acid-secreting parietal cells. Cell Stem Cell , 2024; DOI: 10.1016/j.stem.2024.04.016 Cite This Page : ...

autoimmune gastritis and stomach and esophageal cancers have one thing in common—they involve disruptions of the normal activity of parietal cells (PCs) in the stomach, the only cells in the ...

Common conditions such as indigestion and heartburn as well as peptic ulcers, autoimmune gastritis and stomach and esophageal cancers have one thing in common – they involve disruptions of the normal ...

Achlorhydria from autoimmune parietal-cell destruction may result in concomitant iron deficiency; routine monitoring is warranted. The autoimmune gastritis that underlies pernicious anemia ...

These images are produced using advanced imaging techniques that enable us to study the cells found in the human ... are known to have higher risk for gastrointestinal disease,” Hickey said.