Researchers have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of glucolipotoxicity - a harmful condition linked to the progression of type 2 ...

A naturally occurring molecule that works as effectively as other semaglutide-based drugs — without the common side effects — ...

Scientists have discovered a naturally-occurring molecule that rivals the weight-loss effects of semaglutide-based GLP-1s like Ozempic in animals.

The microbiome shapes the development of insulin-producing cells in infancy, leading to long-term changes in metabolism and ...

Scientists have discovered a naturally-occurring molecule that aids appetite control and weight loss so well, it may compete ...

Murine study identifies critical neonatal window when microbiota disruption results in lifelong metabolic consequences stemming from reduced β cell development.

Researchers have discovered a novel approach to protecting insulin-producing beta cells from the damaging effects of ...

The results could ultimately help doctors reduce the risk of type 1 diabetes—or potentially even restore lost metabolic function in adulthood—by providing gut microbes that help the pancreas grow and ...

ChREBP is a transcription factor that plays a crucial role in regulating glucose metabolism. It exists in two main isoforms: ...

Early-life gut microbes could play a key role in protecting against diabetes. A healthy start for a healthier future.

Although ISECs' precise molecular signatures had been ... a research associate in the Rafii lab. Since pancreatic islets are where insulin is produced, they are also a major focus for diabetes ...