Three key pathways exacerbate NASH when n-6 PUFA is combined with a choline-deficient diet. First, the 15d-PGJ2/PPAR-γ pathway: Reduced 15d-PGJ2 decreases PPAR-γ activation, weakening ...

Objective Enteric glia activation has been reported to amplify intestinal inflammation via the enteroglial-specific S100B protein. This neurotrophin promotes macrophage recruitment in the mucosa, ...

Livdelzi will launch at a list price of $12,606 for a 30-day treatment cycle, a little higher than the $11,500 per month set by Ipsen for Iqirvo, which is a dual PPAR alpha/delta agonist.

EU kicks off review of GSK's linerixibat in PBC. GSK's drug for severe itching in patients with autoimmune liver disease PBC is now under review in the EU and US, as Mirum Pharma tries to catch up.

Discover real-time COMPASS Pathways Plc American Depository Shares (CMPS) stock prices, quotes, historical data, news, and Insights for informed trading and investment decisions. Stay ahead with ...