“The pathophysiology of tumor-induced osteomalacia, driven by increased paraneoplastic production of FGF23, is similar to that of XLH, where renal tubular phosphate wasting occurs due to excess ...

Osteomalacia is a weakening of the bones. When not treated, it can lead to serious health complications, such as fractures and severe deformity. Here, we look at causes, symptoms, diagnosis ...

OSTEOMALACIA is a generalized disease of bone characterized by lack of calcification of a presumably normal osteoid matrix. The chemical changes in the serum are usually diagnostic and consist of ...

The patient (S.M.H. 24–84–09) was born in 1900 without congenital defects. Petit-mal epilepsy developed at the age of 10 years, and frequent grand-mal seizures occurred for the first time in 1924.

Pathology showed features consistent with a phosphaturic mesenchymal tumor. Resection margins were clean, and osteomalacia was present in the surrounding bone tissue.

The word osteomalacia means “soft bones.” The condition keeps your bones from mineralizing, or hardening, as they should. That makes them weak and more likely to bend and break. Only adults ...

Long-term therapy with some antiepileptic drugs and antibiotics can cause osteomalacia, which is usually the result of vitamin D deficiency. University of Washington researchers now report in the ...

The FDA as approved Crysvita® (burosumab-twza; Ultragenyx) for the treatment of fibroblast growth factor 23 (FGF23)-related hypophosphatemia in tumor-induced osteomalacia associated with ...