While opioids interact with numerous cellular pathways, the experimental drug is more selective. SBI-810 targets a receptor ...

Duke scientists may have discovered a game-changing painkiller. SBI-810 is a new non-opioid drug that offers potent pain relief without the addiction, tolerance, or side effects of traditional ...

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The drug also sidesteps common opioid side effects including constipation and sedation. According to the CDC, while opioid deaths decreased significantly in the United States between 2023 and 2024 ...

An experimental drug developed at Duke University School of Medicine could offer powerful pain relief without the dangerous side effects of opioids. The drug, called SBI-810, is part of a new ...

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The researchers found that SBI-810 did not induce common opioid-related side effects such as constipation or tolerance, the latter of which often leads to escalating doses in patients. The compound ...

Scientists have developed a new painkiller that could provide powerful relief without the high caused by opioid drugs.