Here, the authors report regio- and chemoselective nucleophilic aromatic substitution (S N Ar) reactions for the synthesis of heterobiaryl C─N atropisomers, via non-atropisomeric intermediates ...

The design is integrated with TSMC’s Chip-on-Wafer-on-Substrate (CoWoS) packaging technology. This chip builds on the recent release of the Alphawave Semi AI Platform, proving readiness to support the ...

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The catalytic enantioselective synthesis of 3-aryl-substituted pyrrolopyrimidines (PPYs), a common motif in drug discovery, is achieved through a kinetic resolution via quaternary ammonium ...

The reaction of 3-halo-4-aminopyridines with acyl chlorides and triethylamine is described. The pyridin-4-yl α-substituted acetamide products were obtained in moderate to high yields. The presented ...