More and more functions of nucleic acids are discovered in vitro and in cells, such as ribozymes selected to catalyze methylation reactions and ribozymes cutting DNA in genomes. DNA was shown to ...

Resolve Therapeutics, a leader in the emerging field of cell-free nucleic acid therapeutics, today announced a collaboration ...

Download this article to learn how one cell therapy manufacturer optimized PCR-based Mycoplasma testing for in-house use, ...

Figure 3: Activation pathway in plasmacytoid dendritic cells responding to nucleic acids. A recent study however challenges the concept of self versus non-self discrimination based on the presence ...

Innovative delivery techniques, including high-tech nanoparticles and electroporationdevices, may convey more gene therapies into the clinic.

Development of an Elastin-like Polypeptide-Based Nucleic Acid Delivery System Targeted to EGFR+ Bladder Cancer Cells Using a Layer-by-Layer Approach. Biomacromolecules , 2024; DOI: 10.1021/acs ...

Telesis Bio has announced a licensing agreement with Regeneron, enabling the latter to deploy the Gibson SOLA platform at R&D ...

This research sheds light on the complex interactions between nucleic acid sensors and enzymes in immune cells and paves the way for more precise immune therapies.

2 This simple and quick method uses an alkaline solution to lyse the cells and denature proteins and nucleic acids. Upon sample neutralization and genomic DNA precipitation, scientists obtain plasmid ...

A researcher in Purdue University’s College of Science is developing a patent-pending platform technology that mimics the dual-layer structure of viruses to deliver nucleic acid (NA)-based therapies ...