What is it? As the name suggests, nonribosomal peptide synthesis (NRPS) generates polypeptides sans ribosome. The resultant peptides, generally short oligomers of two to perhaps 48 residues, are not ...

question for promising drug targets: ring-shaped nonribosomal peptides. Researchers have invented computational tools to decode and rapidly determine whether natural compounds collected in oceans ...

The synthetic biologists from Imperial College London have re-engineered yeast cells to manufacture the nonribosomal peptide antibiotic penicillin. In laboratory experiments, they were able to ...

rgba(255, 255, 255, 0)”>Such nonribosomal peptides are formed by nonribosomal peptide synthetases (NRPSs) that assemble a diverse group of natural products, including penicillin (antibacterial ...

Most antibiotics are made from nonribosomal peptides, which certain bacteria and fungi naturally produce. As we start running into trouble with the more common antibiotics, there's a need to ...

New research published today in Nature Communications, describes how CRISPR-cas9 gene editing can be used to create new nonribosomal peptide synthetase (NRPS) enzymes that deliver clinically ...

New research published today in Nature Communications, describes how CRISPR-Cas9 gene editing can be used to create new nonribosomal peptide synthetase (NRPS) enzymes that deliver clinically important ...

Re-engineering biosynthetic assembly lines, including nonribosomal peptide synthetases (NRPS) and related megasynthase enzymes, may offer a powerful new route to develop future medicines to combat ...

The synthetic biologists from Imperial College London have re-engineered yeast cells to manufacture the nonribosomal peptide antibiotic penicillin. In laboratory experiments, they were able to ...