Asciminib shows superior tolerability over nilotinib in newly diagnosed CML-CP patients, reducing treatment discontinuation due to adverse effects significantly. Read More. Enhancing Precision in ...

The construction of helical polymer nanotubes with precise structure and enhanced stability remains a formidable challenge in synthetic chemistry, as it requires a complex balance of covalent and ...

Kathleen N. Moore, MD, MS, associate director of clinical research at Stephenson Cancer Center at the College of Medicine of The University of Oklahoma, and coauthors wrote in the presentation, “The ...

AbstractPurpose:. We assessed the safety, maximum tolerated dose, and recommended phase 2 dose (RP2D), efficacy, pharmacokinetics, and pharmacodynamics of the nilotinib–paclitaxel combination in 44 ...

We have established a practical and scalable (>1 g) synthesis of peropyrene, dibenzo[cd,lm]perylene, from easily accessible 2,3-dihydro-1H-phenalen-1-one, which was first dimerized via the reductive ...

Introduction. Although the concept of organic chemistry was proposed before the nineteenth century, the first steps of synthesis analysis took human beings more than 100 years, from 1828, when the ...

Dr. Robert Anthony Holton, known as “Bob” to friends and colleagues, was a groundbreaking chemist and the scientist behind the first total synthesis of the cancer drug Taxol. He died ...

We develop methodology to bridge scenario analysis and risk forecasting, leveraging their respective strengths in policy settings. The methodology, rooted in Bayesian analysis, addresses the ...

The synthesis of new polyhydrides with high superconducting T c is challenging owing to the high pressures and temperatures required. In this study, we used machine-learning potential molecular ...