Another recent success of medicinal chemistry in the sense of structure-based design, iterative synthesis, and analogue testing is the development of inhibitors of KRAS, mutated in up to 30% of all ...

This is a framework for RTL synthesis tools. It currently has extensive Verilog-2005 support and provides a basic set of synthesis algorithms for various application domains. Yosys can be adapted to ...

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One of the key players in mediating pro-inflammatory signaling is the Janus Kinase (JAK) 1/2. Signaling via JAK1/2 and signal transducer and activator of transcription (STAT) pathways are crucial for ...

Cardio-oncology is an emerging interdisciplinary field concerned with cancer treatment-related cardiovascular toxicities (CTR-CVT) and concomitant cardiovascular diseases (CVD) in patients with cancer ...

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